If bugs aren’t annoying enough this summer, trying to figure out which bug spray to use only adds to the irritation. Until now. Bug sprays that work contain one of three ingredients: oil of lemon eucalyptus, picaridin, or DEET. Another compound, permethrin, is sprayed on your clothes, not you, but is very effective against ticks. Whether you’re trying to avoid ticks, which carry Lyme disease, or mosquitos—called the most dangerous animal, due to the number of diseases it can carry (Zika and West Nile Virus, among many others)—here’s what to use.